Element Mapping in Organic Samples Utilizing a Benchtop X-Ray Fluorescence Emission Tomography (XFET) System


X-ray fluorescence computed tomography (XFCT) is an rising imaging modality that maps the 3-dimensional distribution of parts, generally metals, in ex vivo specimens and probably in living animals and humans. Building on our previous synchrotron-primarily based work, we tend to experimentally explored the use of a benchtop X-ray fluorescence computed tomography system for mapping trace-metal ions in biological samples. This method utilizes a scanning pencil beam to stimulate the item and then relies on a detection system, with single or multiple slit apertures placed in front of position-sensitive X-ray detectors, to gather the fluorescence X-rays and to create 3-D elemental map without the requirement for tomographic imaging reconstruction. The technique was used to generate images of the elemental distributions of a triple-tube phantom and an osmium-stained zebrafish.

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