ABSTRACT:

Cell-surface adhesion force is important for cell activities and the development of bio materials. In this paper, a method for in situ single cell $(W303)$ adhesion force measurement was proposed based on nanorobotic manipulation system inside an environment scanning electron microscope (ESEM). An end effector was fabricated from a commercial atomic force microscope (AFM) cantilever by focused ion beam (FIB) etching. The spring constant of it was calibrated by nanomanipulation approach. Three kinds of hydrophilic and hydrophobic ITO plates were prepared by using VUV-irradiation and OTS coating techniques. The shear adhesion strength of the single yeast cell to each substrate was measured based on the deflection of the end effector. The results demonstrated that the cell adhesion force was larger under the wet condition in the ESEM environment than in the aqueous condition. It also showed that the cell adhesion force to hydrophilic surface was larger than that to the hydrophobic surface. Studies of single cell's adhesion on various plate surfaces and environments could give new insights into the tissue engineering and biological field.


Did you like this research project?

To get this research project Guidelines, Training and Code... Click Here


PROJECT TITLE : Development and Assessment of a New Global Mammographic Image Feature Analysis Scheme to Predict Likelihood of Malignant Cases ABSTRACT: Researchers in this project hope to create and test a new computer-aided
PROJECT TITLE : Efficient Evaluation of Image Quality via Deep-Learning Approximation of Perceptual Metrics ABSTRACT: An important role in the evaluation of complicated image processing algorithms is played by image metrics based
PROJECT TITLE : Tensor Oriented No-Reference Light Field Image Quality Assessment ABSTRACT: Immersive media acquisition, processing, and application are becoming more dependent on the quality of light field images (LFIs). A multi-dimensional
PROJECT TITLE :Massive Streaming PMU Data Modelling and Analytics in Smart Grid State Evaluation based on Multiple High-Dimensional Covariance Test - 2018ABSTRACT:Analogous deployment of part measurement units (PMUs), the increase
PROJECT TITLE :Complex Queries Optimization and Evaluation over Relational and NoSQL Data Stores in Cloud Environments - 2018ABSTRACT:The production of giant quantity of data and the emergence of cloud computing have introduced

Ready to Complete Your Academic MTech Project Work In Affordable Price ?

Project Enquiry