PROJECT TITLE :

Magnetophoretic Velocity Determined by Space- and Time-Resolved Extinction Profiles

ABSTRACT:

Magnetophoretic velocity of magnetic nano-objects for biomedical applications was characterized by measuring area- and time-resolved extinction profiles (STEP-Technology) employing a customized LUMiReader device equipped with a group of permanent magnets (STEP-MAGAZINE). The resulting magnetic fields and gradients in a sample volume enable the operator to settle on measurement conditions for magnetic micro- and nanoparticles and their assemblies. The dependence of magnetophoretic velocity on concentration and optical wavelengths indicated assembly of the nano-objects upon magnetophoresis. The method has potential applications in biomedicine to develop advanced materials and protocols for cell separation, tissue engineering, and drug/nucleic acid targeting.