PROJECT TITLE :

Development of Novel Implantable Intraocular Pressure Sensors to Enhance the Performance in in vivo Tests

ABSTRACT:

In this paper, we tend to proposed a dual-mode intraocular pressure (IOP) sensor that has two separated diaphragms to conduct the changes of inductance and capacitance, and we compared the sensor’s performance with that of the traditional single variable capacitive sensor (single-mode sensor). Each mode sensors were used to watch the pressure in in vitro tests with multiple media and in in vivo tests with rabbits. 1st, we tend to demonstrated that the sensitivities of two sorts of sensors tended to be different for in vivo and in vitro tests. This was the first known attempt to point out changes in the sensitivity and responsivity of IOP sensors in in vivo tests. The sensitivity and part DIP of the twin-mode sensor exceeded that of the single-mode sensor, no matter medium because of isolation of capacitive sensor from medium. During this paper, we have a tendency to have provided the equations that were used to guage the development in sensitivity, and we have shown the coincidence with in vitro and in vivo tests. Based on the results we achieved, we tend to believe that the dual-mode sensor is additional feasible to be used as an IOP sensor in in vivo tests, as a result of its responsivity and sensitivity are superior to those of the conventional sensors. [2014-0379]