Hardware-Acceleration of Short-Read Alignment Based on the Burrows-Wheeler Transform PROJECT TITLE :Hardware-Acceleration of Short-Read Alignment Based on the Burrows-Wheeler TransformABSTRACT:The alignment of several short DNA fragments to a giant genome may be a terribly important facet of the trendy computational biology. But, software-primarily based DNA sequence alignment takes many hours to finish. This paper proposes an FPGA-based mostly hardware accelerator to reduce the alignment time. We tend to apply a knowledge encoding theme that reduces the info size by 96 %, and propose a pipelined hardware decoder to decode the info. We have a tendency to additionally style customized knowledge paths to efficiently use the restricted bandwidth of the DDR3 memories. The proposed accelerator can align a few hundred million short DNA fragments in an hour by using eighty processing parts in parallel. The proposed accelerator has the identical mapping quality compared to the software-primarily based strategies. Did you like this research project? To get this research project Guidelines, Training and Code... Click Here facebook twitter google+ linkedin stumble pinterest Reliability Analysis for Repairable Multistate Two-Unit Series Systems When Repair Time Can Be Neglected Anonymity and Fairness in Packet Scheduling: A Quantitative Tradeoff
