PROJECT TITLE :
Design and Simulation of Proportional Biological Operational Mu-Circuit
It is difficult nonetheless fascinating to quantitatively control the expression of a target gene in practice. We design a tool-Proportional Biological Operational Mu-circuit (P-BOM) incorporating AND/OR gate and operational amplifier into one circuit and explore its behaviors through simulation. The results imply that will be doable to control input-output proportionally by manipulating the RBS of hrpR, hrpS, tetR and output gene and employed in the sensing of environmental weak signals like dioxins.
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