PROJECT TITLE :

A Non-Magnetic Rotating Disk Stimulator for the Study of Neuromagnetic Correlates of Sensorimotor Interaction

ABSTRACT:

Fine motor skills in humans require shut interaction between the motor and also the sensory systems. It's still not fully understood, how sensory feedback modulates motor commands. This is due to the actual fact, that there is no approach for investigating the sensorimotor cortical-interaction in sufficient detail. The quick and precise communication between the sensory and motor-systems needs measurements of cortical activity with high temporal and spatial resolution. Magnetoencephalography (MEG) is capable of each. Previously, we showed that sensory responses, will be observed by repetitive tactile stimulation. More, motor cortex responses will be generated by periodical increase and decrease of muscle tone. Utilizing each observations we tend to have designed an MEG and magnetic resonance imaging (MRI) compatible stimulator permitting for the study of brain activity related to sensorimotor integration. The stimulator consists of a rotating disk with an elevation such that subject senses with his finger the speed of the disk. With the force applied by the finger onto the disk, the topic will control its speed. Throughout the experiment the topic is asked to keep the speed of the disk constant whereas the driving torque is systematically manipulated. This closed-loop style is especially helpful to research the fast and continuous info flow between the 2 systems. In an exceedingly single case pilot study using MEG, we have a tendency to could show that a detailed analysis of the sensorimotor-network is doable. In distinction to existing paradigms this setup allows separate time-locked analysis of the sensory- and motor-part independently and so the calculation of latency parameters for both systems. In the long run this methodology can help to perceive the interaction between the 2 systems in a lot of greater detail.


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