PROJECT TITLE :

A versatile and experimentally validated finite element model to assess the accuracy of shear wave elastography in a bounded viscoelastic medium

ABSTRACT:

The feasibility of shear wave elastography (SWE) in arteries for cardiovascular risk assessment remains to be investigated as the artery's skinny wall and complicated material properties induce advanced shear wave (SW) propagation phenomena. To better understand the SW physics in bounded media, we proposed an in vitro validated finite component model capable of simulating SW propagation, with full flexibility at the level of the tissue's geometry, material properties, and acoustic radiation force. This laptop model was presented in a very relatively basic set-up, a homogeneous slab of gelatin-agar material (4.thirty five mm thick), allowing validation of the numerical settings per actual SWE measurements. The resulting tissue velocity waveforms and SW propagation speed matched well with the measurement: four.forty six m/s (simulation) versus four.63 ?? zero.07 m/s (experiment). More, we have a tendency to identified the impact of geometrical and material parameters on the SW propagation characteristics. As expected, phantom thickness was a determining issue of dispersion. Adding viscoelasticity to the model augmented the estimated wave speed to four.fifty eight m/s, an even better match with the experimental determined worth. This study demonstrated that finite component modeling can be a powerful tool to realize insight into SWE mechanics and will in future work be advanced to additional clinically relevant settings.


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