PROJECT TITLE :
Simultaneous Multi-Scale Diffusion Estimation and Tractography Guided by Entropy Spectrum Pathways
We have developed a technique for the simultaneous estimation of local diffusion and the global fiber tracts based upon the data entropy flow that computes the most entropy trajectories between locations and depends upon the global structure of the multi-dimensional and multi-modal diffusion field. Computation of the entropy spectrum pathways needs solely solving a simple eigenvector problem for the chance distribution for that economical numerical routines exist, and a easy integration of the likelihood conservation through ray tracing of the convective modes guided by a international structure of the entropy spectrum coupled with a little scale local diffusion. The intervoxel diffusion is sampled by multi b-shell multi q-angle diffusion weighted imaging knowledge expanded in spherical waves. This novel approach to fiber tracking incorporates international information regarding multiple fiber crossings in every individual voxel and ranks it in the most scientifically rigorous means. This method has potential significance for a wide range of applications, including studies of brain connectivity.
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