CMOS-based implantable glucose monitoring device with improved performance and reduced invasiveness


An implantable glucose monitoring device based on a CMOS line sensor combined with a glucose-responsive fluorescent hydrogel is developed. An implantable glucose monitoring device with sufficient sensitivity and response time is realised, which is an improvement over the authors' previous proof-of-concept device. A reduction of the sensor size created the device diameter injectable with a commercially on the market 16-gauge syringe needle. The sensor's performance was confirmed through each in vitro and in vivo experiments.

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