Low auto-fluorescence fabrication methods for plastic nanoslits


Plastic nanofluidic devices are changing into increasingly necessary for biological and chemical applications. However, they suffer from high auto-fluorescence when used for on-chip optical detection. In this study, the auto-fluorescence drawback of plastic nanofluidic devices was remedied by newly developed fabrication ways that minimise their auto-fluorescence: one by depositing a gold (Au) layer on them, the opposite by creating them ultra-thin. In the primary technique, the Au layer [minimum thickness is 40 nm on 150 μm SU-eight, fifty nm on 1 mm polyethylene terephthalate (PET), and forty on two nm polymethyl methacrylate (PMMA)] blocks the auto-fluorescence of the polymer; within the second technique, auto-fluorescence is minimised by making the chips ultra-skinny, selected operating thickness of SU-8 is 20 μm, for PET it is a hundred and fifty μm, and for PMMA it is zero.eight mm.

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