PROJECT TITLE :
Computational Study Toward Deep Transcranial Magnetic Stimulation Using Coaxial Circular Coils
Objective: To investigate the chance for exciting deeper brain regions while decreasing the electrical field in superficial cortical regions by using coaxial circular coils. Strategies: The Halo coil, Halo-circular assembly coil (HCA coil) and Halo coil working with 2 circular coils (HTC coil) were applied over a 36-tissue anatomically primarily based head model. 3-dimensional distributions of magnetic flux density, induced electric field in head tissues were obtained by 3-D impedance method. Results: For the case of HCA coil with current flowing in the identical direction in every of 2 coils, the field penetration depth by the conventional circular coil can be effectively increased at the expense of reduced focality. For the case of the HTC coil with currents flowing in other way in the neighboring coils, overthreshold electric fields can be created in deep brain regions, whereas the subthreshold fields were made in superficial cortical areas. Conclusion: The HTC coil with varied coil parameters and totally different injected currents provides a flexible means for deep brain stimulation with better ratio of deep region field relative to field at the shallow areas. Significance: The HTC coil is promising for deep transcranial magnetic stimulation, that may supply a replacement tool with potential for both analysis and clinical applications for psychiatric and neurological disorders associated with dysfunctions of deep brain regions.
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